SHIFTING PARADIGMS
IN ONCOLOGY

Volastra targets chromosomal instability,
signaling a new era in cancer treatment

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References:

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  2. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature. 1998;396(6712):643-649.
  3. Bakhoum SF, Cantley LC. The multifaceted role of chromosomal instability in cancer and its microenvironment. Cell. 2018;174(6):1347-1360.
  4. Primo LMF, Teixeira LK. DNA replication stress: oncogenes in the spotlight. Genet Mol Bio. 2020;43(1)(suppl 1):1-14.